Preacher 25th Anniversary graphic novel omnibus volume 2 contains Preacher issues #34-66, Preacher Special: The Story of You-Know-Who, Preacher Special: The Good Old Boys, Preacher Special: One Man's War, Preacher: Tall in the Saddle and material from Absolute Preacher volumes 2 and 3, and features story by Garth Ennis and art by Steve Dillon.

Beginning with the “War in the Sun” story, Texan preacher Jesse Custer goes to Monument Valley, where he plans his showdown with God. But Starr and the Saint of Killers have other plans for Jesse’s future.

Merging with a bizarre spiritual force called Genesis, Jesse becomes completely disillusioned with the beliefs that he had dedicated his entire life to. Now possessing the power of “the Word,” an ability to make people obey whatever he utters, Custer sets off on a dark journey. He loses faith in both humanity and God as he witnesses atrocities and improbable calamities during his travels. Jesse is joined by his gun-toting girlfriend, Tulip, and the hard-drinking Irish vampire, Cassidy, on the rowdy adventures that culminate in the High Noon to end all High Noons.

Included in this omnibus are specials featuring the origins of Arseface, the dastardly adventures of Jody and T.C.—the animal-loving henchmen employed by Jesse Custer’s grandma—Jesse and Tulip’s early days of love, and much, much more.