Manhole manga volume 2 features story and art by Tetsuya Tsutsui.

The situation is critical: For reasons unknown, mosquitoes carrying the filariasis parasite are still active, despite the winter season. Their proliferation brings the risk of a terrifying increase in the number of victims.

With the possibility of a pandemic looming, Inspector Mizoguchi determinedly follows the trail of his number one suspect. But when he's exposed to an infected individual, he's suddenly racing against the clock. Will he survive long enough to solve the mystery?